Sterols and their biosynthesis in some freshwater bivalves

S Popov; I Stoilov; N Marekov; G Kovachev; S Andreev

doi:10.1007/BF02535061

Sterols and their biosynthesis in some freshwater bivalves

Lipids. 1981 Sep;16(9):663-9. doi: 10.1007/BF02535061.

Authors

S Popov¹, I Stoilov¹, N Marekov¹, G Kovachev², S Andreev³

Affiliations

¹ Institute of Organic Chemistry and Centre of Phytochemistry, Bulgarian Academy of Sciences, 1113, Sofia, Bulgaria.
² Research Institute of Mineral Resources, 1113, Sofia, Bulgaria.
³ Museum of Natural History, 1000, Sofia, Bulgaria.

PMID: 27519234
DOI: 10.1007/BF02535061

Abstract

A number of free sterols and sterol esters of three freshwater mussels was separated and identified. A slow rate of biosynthesisde novo of sterols was demonstrated inAnodonta cygnea. Injected cholesterol was found to undergo esterification, oxidation, Δ(22)-dehydrogenation and C-24 alkylation. Methyl-[(14)C]methionine was proved to be incorporated in C-24 alkylsterols. Abnormally large amounts of cholesterol injected inA. cygnea were metabolized toward restoration of the normal composition of sterols. This was achieved by intensified metabolism of cholesterol, mainly by conjugation, oxidation and Δ(22)-dehydrogenation.