Variations in seroprevalences of canine leishmaniasis: Could it be a consequence of the population structure?

Vet Parasitol. 2016 Aug 15:226:5-9. doi: 10.1016/j.vetpar.2016.06.018. Epub 2016 Jun 14.

Abstract

Canine leishmaniasis is a parasitic disease caused by Leishmania infantum and is transmitted by Phlebotominae vectors. Despite numerous publications on the subject, some essential aspects of the epidemiology are not yet sufficiently clear. We proposed a stochastic model with the aim of identifying some important gaps in the current knowledge of leishmaniasis, such as the frequency of vector infection or a dog's life expectancy depending on their purpose and their health status. We only found that the purpose was a significant factor. Furthermore, we detected relationships among age, gender and habitat with the dogs' purposes that can affect the calculation of the overall seroprevalence of the analysed sample. The development of this model will allow us to discard potential confounding factors as gender, age, purpose or habitat.

Keywords: Epidemiology; Leishmania infantum; Modelling; Population dynamics; Seroprevalence.

Publication types

  • Observational Study

MeSH terms

  • Age Factors
  • Animals
  • Antibodies, Protozoan / blood
  • Chi-Square Distribution
  • Computer Simulation
  • Confounding Factors, Epidemiologic
  • Cross-Sectional Studies
  • Dog Diseases / epidemiology*
  • Dog Diseases / parasitology*
  • Dogs
  • Female
  • Leishmania / immunology*
  • Leishmaniasis / epidemiology
  • Leishmaniasis / veterinary*
  • Logistic Models
  • Male
  • Models, Biological
  • Rural Population
  • Seroepidemiologic Studies
  • Sex Distribution
  • Spain / epidemiology
  • Stochastic Processes
  • Urban Population

Substances

  • Antibodies, Protozoan