Phenolic content, antioxidant capacity and antimicrobial activity of leaf extracts from Pistacia atlantica

Nat Prod Res. 2017 Mar;31(6):696-699. doi: 10.1080/14786419.2016.1212035. Epub 2016 Aug 3.

Abstract

The aim of this study was to investigate the secondary metabolites related to Pistacia atlantica Desf as well as their biological activities. Results show that using ethanol as a solvent exhibited the highest content of total phenolics and flavonoids (68.23 mg GAE g-1 of DW and 44 mg RE g-1 of DW), followed by aqueous one (20.07 mg GAE g-1 of DW and 15 mg RE g-1 of DW). Good correlation (Data not shown) was obtained between the DPPH radical-scavenging activities and total phenolics contents. Many similarities were observed between the results of the DPPH (IC50 = 32 and 200 μg mL-1) and ABTS (IC50 = 42 and 300 μg mL-1) assays. All tested extracts contained phenolic compounds exhibited an antimicrobial effect against Gram-positive and Gram-negative bacteria. Further, researches for identification and purification of phenolic compounds are required.

Keywords: DPPH; Pistacia atlantica Desf; medicinal plants; phenolic compounds.

MeSH terms

  • Anti-Infective Agents / chemistry*
  • Anti-Infective Agents / pharmacology*
  • Antioxidants / chemistry*
  • Antioxidants / pharmacology*
  • Benzothiazoles / chemistry
  • Biphenyl Compounds / chemistry
  • Ethanol
  • Gram-Negative Bacteria / drug effects
  • Gram-Positive Bacteria / drug effects
  • Microbial Sensitivity Tests
  • Phenols / chemistry*
  • Phenols / pharmacology*
  • Picrates / chemistry
  • Pistacia / chemistry*
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology*
  • Plant Leaves / chemistry*
  • Solvents
  • Sulfonic Acids / chemistry

Substances

  • Anti-Infective Agents
  • Antioxidants
  • Benzothiazoles
  • Biphenyl Compounds
  • Phenols
  • Picrates
  • Plant Extracts
  • Solvents
  • Sulfonic Acids
  • 2,2'-azino-di-(3-ethylbenzothiazoline)-6-sulfonic acid
  • Ethanol
  • 1,1-diphenyl-2-picrylhydrazyl