How to Deal with Batch Effect in Sequential Microarray Experiments?

Mol Inform. 2010 May 17;29(5):387-93. doi: 10.1002/minf.200900019. Epub 2010 May 14.

Nino Demetrashvili^{1

2}, Ken Kron^{2

3}, Vaijayanti Pethe^{2

4}, Bharati Bapat^{2

3

4}, Laurent Briollais^{5

6}

¹ Dalla Lana School of Public Health, University of Toronto, Toronto M5T 3M7, Ontario Canada.
² Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto M5G 1X5, Ontario Canada.
³ Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto M5G 1A8, Ontario Canada.
⁴ Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto M5G 1X5, Ontario Canada.
⁵ Dalla Lana School of Public Health, University of Toronto, Toronto M5T 3M7, Ontario Canada. laurent@lunenfeld.ca.
⁶ Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Toronto M5G 1X5, Ontario Canada. laurent@lunenfeld.ca.

No abstract available

Keywords: Batch effect adjustment; Clustering; Empirical Bayes; Methylation profile; Sequential microarray experiments.