[Research progress on molecular genetics of male homosexuality]

Dan Tu; Ruiwei Xu; Guanglu Zhao; Binbin Wang; Tiejian Feng

doi:10.3760/cma.j.issn.1003-9406.2016.04.032

[Research progress on molecular genetics of male homosexuality]

Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2016 Aug;33(4):569-72. doi: 10.3760/cma.j.issn.1003-9406.2016.04.032.

[Article in Chinese]

Authors

Dan Tu¹, Ruiwei Xu, Guanglu Zhao, Binbin Wang, Tiejian Feng

Affiliation

¹ Shenzhen Center for Chronic Disease Control, Shenzhen, Guangdong 518020, China; College of Life Science, Shenzhen University, Shenzhen, Guangdong 518060, China; School of Public Health, Central South University, Changsha, Hunan 410083, China; National Research Institute for Family Planning, Beijing 100081, China. Email: fengtiej@126.com.

PMID: 27455023
DOI: 10.3760/cma.j.issn.1003-9406.2016.04.032

Abstract

Sexual orientation is influenced by both environmental factors and biological factors. Family and twin studies have shown that genetic factors play an important role in the formation of male homosexuality. Genome-wide scan also revealed candidate chromosomal regions which may be associated with male homosexuality, but so far no clearly related genes have been found. This article reviews the progress of relevant studies and candidate genes which are related to male homosexuality.

Publication types

English Abstract
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Aromatase / genetics
Catechol O-Methyltransferase / genetics
Homosexuality, Male / genetics*
Humans
LIM-Homeodomain Proteins / genetics
Male
Receptors, Dopamine D1 / genetics
Transcription Factors / genetics

Substances

DRD1 protein, human
LIM homeobox transcription factor 1 beta
LIM-Homeodomain Proteins
Receptors, Dopamine D1
Transcription Factors
Aromatase
Catechol O-Methyltransferase