Identification of the novel B*27:144 allele in an Irish Individual

HLA. 2016 Jul;88(1-2):47-8. doi: 10.1111/tan.12846. Epub 2016 Jul 25.

Abstract

The sequence of HLA-B*27:144 differs from HLA-B*27:05:02 by one nucleotide change at position 506.

Keywords: HLA-B*27:144; New allele; single molecule real time sequencing.

MeSH terms

  • Alleles*
  • Amino Acid Substitution
  • Base Sequence
  • Exons*
  • Gene Expression
  • Genotype
  • HLA-B27 Antigen / genetics*
  • HLA-B27 Antigen / immunology
  • Histocompatibility Testing
  • Humans
  • Ireland
  • Point Mutation*
  • Sequence Alignment
  • Sequence Analysis, DNA

Substances

  • HLA-B27 Antigen