The role of interleukin 5 in asthma

Expert Rev Clin Immunol. 2016 Sep;12(9):903-5. doi: 10.1080/1744666X.2016.1208564. Epub 2016 Jul 25.

Authors

Gilda Varricchi¹, Giorgio W Canonica²

Affiliations

¹ a Department of Translational Medical Sciences, Division of Clinical Immunology and Allergy , University of Naples Federico II , Napoli , Italy.
² b Allergy & Respiratory Diseases, DIMI Dept of Internal Medicine , University of Genoa, IRCCS AOU San Martino-IST , Genoa , Italy.

PMID: 27450970
DOI: 10.1080/1744666X.2016.1208564

No abstract available

Keywords: IL5; asthma; eosinophils; interleukins; monoclonals.

Publication types

Editorial

MeSH terms

Antibodies, Monoclonal, Humanized / immunology
Antibodies, Monoclonal, Humanized / therapeutic use
Asthma / drug therapy
Asthma / immunology*
Asthma / metabolism
Eosinophilia / drug therapy
Eosinophilia / immunology*
Eosinophilia / metabolism
Eosinophils / drug effects
Eosinophils / immunology
Eosinophils / metabolism
Humans
Interleukin-5 / antagonists & inhibitors
Interleukin-5 / immunology*
Interleukin-5 / metabolism
Interleukin-5 Receptor alpha Subunit / antagonists & inhibitors
Interleukin-5 Receptor alpha Subunit / immunology
Interleukin-5 Receptor alpha Subunit / metabolism
Signal Transduction / drug effects
Signal Transduction / immunology*

Substances

Antibodies, Monoclonal, Humanized
IL5 protein, human
IL5RA protein, human
Interleukin-5
Interleukin-5 Receptor alpha Subunit
reslizumab
benralizumab
mepolizumab