Laboratory tests as short-term correlates of stroke

BMC Neurol. 2016 Jul 21:16:112. doi: 10.1186/s12883-016-0619-y.

Abstract

Background: The widespread adoption of electronic health records provides new opportunities to better predict which patients are likely to suffer a stroke. Using electronic health records, we assessed the correlation of different laboratory tests to future occurrences of a stroke.

Methods: We examined the electronic health records of 2.4 million people over a two year time span. These records contained 26,964 diagnoses of stroke. Using Cox regression analysis, we measured whether any one of 1796 different laboratory tests were effectively correlated with a future diagnosis of stroke.

Results: We identified 38 different laboratory tests that had significant short-term (two year) prognostic value for a future diagnosis of stroke. For each of the 38 laboratory tests we also compiled the Kaplan-Meier survival curve, and relative risk ratio that the test confers.

Conclusion: Several dozen laboratory tests are effective short-term correlates of stroke.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Blood Cell Count / statistics & numerical data
  • Blood Chemical Analysis / statistics & numerical data
  • California / epidemiology
  • Cholesterol / blood
  • Cholesterol, HDL / blood
  • Cholesterol, LDL / blood
  • Clinical Laboratory Techniques / statistics & numerical data*
  • Cohort Studies
  • Electronic Health Records / statistics & numerical data
  • Female
  • Forecasting
  • Heart Rate
  • Humans
  • Male
  • Middle Aged
  • Prognosis
  • Retrospective Studies
  • Stroke / epidemiology*
  • Survival Rate
  • Young Adult

Substances

  • Cholesterol, HDL
  • Cholesterol, LDL
  • Cholesterol