[Primary cutaneous B-cell lymphomas: study of 22 cases]

Abstract

Introduction and objectives: Primary cutaneous B-cell lymphoma (CBCL) is a very low prevalence neoplasm and constitutes 25% of all primary cutaneous lymphomas. Our objective was to discover the epidemiological, clinic and histologic characteristics of CBCL in our area.

Methods: Retrospective descriptive study with patients with histologic diagnosis of CBCL followed up in our department between 2004 and 2015.

Results: Twenty-two patients with CBCL were included; 65% were men and 35% were women. Follicle centre lymphoma was the most common subtype (41%). Only 3 cases presented with node involvement and one with bone marrow invasion. Five recurrences were detected and one patient died because of the CBCL.

Discussion and conclusions: This is one of the first CBCL series in theSpanish population. The incidence, sex, age, subtype distribution, clinical features and immunohistochemical patterns are very similar to those of the other series.

Keywords: B-cell cutaneous lymphoma; Follicle centre lymphoma; Linfoma B cutáneo; Linfoma cutáneo centrofolicular; Linfoma cutáneo tipo pierna; Linfoma cutáneo zona marginal; Primary cutaneous diffuse large b-cell lymphoma leg-type; Primary cutaneous marginal zone lymphoma.