Neuromechanical interactions between the limbs during human locomotion: an evolutionary perspective with translation to rehabilitation

Exp Brain Res. 2016 Nov;234(11):3059-3081. doi: 10.1007/s00221-016-4715-4. Epub 2016 Jul 15.

Abstract

During bipedal locomotor activities, humans use elements of quadrupedal neuronal limb control. Evolutionary constraints can help inform the historical ancestry for preservation of these core control elements support transfer of the huge body of quadrupedal non-human animal literature to human rehabilitation. In particular, this has translational applications for neurological rehabilitation after neurotrauma where interlimb coordination is lost or compromised. The present state of the field supports including arm activity in addition to leg activity as a component of gait retraining after neurotrauma.

Keywords: CNS; Evolution; Neuroscience; Primate; Reflex; Rehabilitation; Walking.

Publication types

  • Review

MeSH terms

  • Animals
  • Biological Evolution*
  • Brain Diseases / complications
  • Brain Diseases / metabolism
  • Extremities / physiology*
  • Gait Disorders, Neurologic / etiology
  • Gait Disorders, Neurologic / rehabilitation*
  • Humans
  • Locomotion / physiology*
  • Translational Research, Biomedical*