Design and rationale of the STRIVE trial to improve cardiometabolic health among children and families

Nicolas M Oreskovic; Richard Fletcher; Mona Sharifi; John D Knutsen; Ani Chilingirian; Elsie M Taveras

doi:10.1016/j.cct.2016.07.012

Design and rationale of the STRIVE trial to improve cardiometabolic health among children and families

Contemp Clin Trials. 2016 Jul:49:149-54. doi: 10.1016/j.cct.2016.07.012. Epub 2016 Jul 11.

Authors

Nicolas M Oreskovic¹, Richard Fletcher², Mona Sharifi³, John D Knutsen⁴, Ani Chilingirian⁵, Elsie M Taveras⁶

Affiliations

¹ Division of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, MA, USA; Department of Internal Medicine, Massachusetts General Hospital, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: noreskovic@mgh.harvard.edu.
² Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: fletcher@media.mit.edu.
³ Division of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: msharifi@mgh.harvard.edu.
⁴ Division of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, MA, USA; Harvard Medical School, Boston, MA, USA. Electronic address: jknutsen@mgh.harvard.edu.
⁵ Media Lab, Massachusetts Institute of Technology, Cambridge, MA, USA. Electronic address: anic@mit.edu.
⁶ Division of General Academic Pediatrics, Department of Pediatrics, MassGeneral Hospital for Children, Boston, MA, USA; Harvard Medical School, Boston, MA, USA; Department of Nutrition, Harvard T.H. Chan School of Public Health, Boston, MA, USA. Electronic address: etaveras@mgh.harvard.edu.

Abstract

Background: Many of the health behaviors known to contribute to cardiometabolic risk and disease (CMRD), including physical activity, diet, sleep, and screen time, begin during childhood. Given the population-wide burden of CMRD, novel ways of assessing risk and providing feedback to support behavior change are needed.

Purpose: This paper describes the design and rationale for the Study for using Technology to Reach Individual Excellence (STRIVE), a randomized controlled trial testing the use of an integrated, closed-loop feedback system that incorporates longitudinal, patient-generated, mobile health technology (mHealth) data on health behaviors and provides clinical recommendations to help manage CMRD among at-risk families.

Methods: STRIVE is a 6-month trial among 68 children, ages 6-12year olds with a body mass index≥85th percentile from Massachusetts with at least one parent with CMRD. Data on several health behaviors will be collected daily over 6months. Children and parents will each wear wristbands that collect objective physical activity, sleep, and screen time data via accelerometry, noise, and infrared detection. Sugar sweetened beverage consumption will be assessed by self-report via a smartphone application. Weight will be collected using a wireless scale. Intervention group parents receive feedback on their child's health behaviors and personalized CMRD counseling via mobile messaging. Control parents receive standard of care recommendations and weekly health behavior reports for self-guided care.

Conclusion: The STRIVE trial will test the use of mHealth and closed-loop feedback systems to improve health behaviors among families at-risk for or with established CMRD.

Keywords: Cardiometabolic; Childhood; Health behaviors; Obesity; Technology; mHealth.

Publication types

Randomized Controlled Trial
Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Accelerometry
Child
Family
Feasibility Studies
Feedback*
Health Behavior*
Health Promotion / methods*
Humans
Overweight / rehabilitation
Pediatric Obesity / rehabilitation*
Telemedicine*

Abstract

Publication types

MeSH terms

Grants and funding