Persister Awakening

Kim Lewis; Yue Shan

doi:10.1016/j.molcel.2016.06.025

Persister Awakening

Mol Cell. 2016 Jul 7;63(1):3-4. doi: 10.1016/j.molcel.2016.06.025.

Authors

Kim Lewis¹, Yue Shan²

Affiliations

¹ Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA 02115, USA. Electronic address: k.lewis@neu.edu.
² Antimicrobial Discovery Center, Department of Biology, Northeastern University, Boston, MA 02115, USA.

PMID: 27392143
DOI: 10.1016/j.molcel.2016.06.025

Abstract

In this issue of Molecular Cell, Cheverton et al. (2016) report that Samonella toxin TacT contributes to persister formation by acetylating tRNA, a novel mechanism of toxin action. Hydrolyzing corrupted tRNA resuscitates persisters.

Publication types

Comment

MeSH terms

Anti-Bacterial Agents*
Endotoxins*

Substances

Anti-Bacterial Agents
Endotoxins
salmonella toxin