Intrathyroidal parathyroid adenoma: Diagnostic pitfalls on fine-needle aspiration: Two case reports and literature review

Diagn Cytopathol. 2016 Nov;44(11):921-925. doi: 10.1002/dc.23528. Epub 2016 Jul 8.

Abstract

Parathyroid adenomas may occur within the thyroid, clinically simulating thyroid nodules. Fine-needle aspiration (FNA) of these presumably "thyroid nodules" can lead to misinterpretation of cytomorphological findings because of similarities in cytological features of parathyroid and thyroid lesions. Here, we reported two cases of intrathyroidal parathyroid adenomas. One of them was misinterpreted as thyroid lesions. The other was composed exclusively of oncocytic cells and had a correct cytological diagnosis. In this study, both cases showed a new cytological feature which has not been reported in the literature: many capillaries protruding outside the three-dimensional fragments without epithelial cells around. Diagn. Cytopathol. 2016;44:921-925. © 2016 Wiley Periodicals, Inc.

Keywords: case report; diagnostic pitfall; fine-needle aspiration; intrathyroidal parathyroid adenoma.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adenoma / pathology*
  • Biopsy, Fine-Needle
  • Diagnosis, Differential
  • Diagnostic Errors
  • Female
  • Humans
  • Middle Aged
  • Parathyroid Neoplasms / pathology*
  • Thyroid Nodule / pathology*