Animal experiments for the determination of an optimal wavelength for retinal coagulations

Graefes Arch Clin Exp Ophthalmol. 1989;227(3):277-80. doi: 10.1007/BF02172762.

Abstract

The retina of rabbits was coagulated with different wave-lengths (570-630 nm) using a tunable dye laser with Rhodamin 6G. To achieve comparable ophthalmoscopic appearance the intensity of the laser beam was varied with neutral filters of varying absorption. Histologic examination of fresh coagulation effects and 3-week-old coagulation scars showed no difference in relation to the wave-length used. Theoretically, 577 nm seems to be a particularly useful wavelength for the treatment of a wide variety of retinal lesions because it is not absorbed in xanthophyll and penetrates opacities of the optic media better than argon blue green. Furthermore, it is absorbed maximally in hemoglobin, making it particularly suitable for the coagulation of blood vessels.

MeSH terms

  • Animals
  • Edema / pathology
  • Fundus Oculi
  • Lasers / standards*
  • Light Coagulation*
  • Pigment Epithelium of Eye / pathology
  • Rabbits
  • Retina / pathology
  • Retina / surgery*
  • Time Factors