Visible Light-Induced Radical Rearrangement to Construct C-C Bonds via an Intramolecular Aryl Migration/Desulfonylation Process

Yuyuan Li; Bei Hu; Wuheng Dong; Xiaomin Xie; Jun Wan; Zhaoguo Zhang

doi:10.1021/acs.joc.6b00735

Visible Light-Induced Radical Rearrangement to Construct C-C Bonds via an Intramolecular Aryl Migration/Desulfonylation Process

J Org Chem. 2016 Aug 19;81(16):7036-41. doi: 10.1021/acs.joc.6b00735. Epub 2016 Jul 7.

Authors

Yuyuan Li¹, Bei Hu², Wuheng Dong², Xiaomin Xie², Jun Wan¹, Zhaoguo Zhang²

Affiliations

¹ Key Laboratory of Sensor Analysis of Tumor Marker, Ministry of Education, College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology , Qingdao 266042, China.
² School of Chemistry and Chemical Engineering, Shanghai Jiao Tong University , 800 Dongchuan Road, Shanghai, 200240, China.

PMID: 27351977
DOI: 10.1021/acs.joc.6b00735

Abstract

A highly efficient intramolecular selective aryl migration/desulfonylation of 2-bromo-N-aryl-N-(arenesulfonyl)amide via visible light-induced photoredox catalysis has been accomplished. This approach allows for the construction of a variety of multisubstituted N,2-diarylacetamide under mild reaction conditions.

Publication types

Research Support, Non-U.S. Gov't