Lithium-Induced Downbeat Nystagmus and Horizontal Gaze Palsy

Open Ophthalmol J. 2016 Apr 29:10:126-8. doi: 10.2174/1874364101610010126. eCollection 2016.

Abstract

We report a case of lithium-induced downbeat nystagmus and horizontal gaze palsy in a 62-year-old woman who was treated for a bipolar affective disorder with lithium carbonate for one month. At presentation serum lithium was within therapeutic range. No alternative causes of the ocular motility disturbances were found, and the patient improved significantly as lithium carbonate was discontinued.

Keywords: Adverse effects; Downbeat nystagmus; Gaze palsy; Lithium.