The benefit of exercise training in pulmonary hypertension: a clinical review

Intern Med J. 2017 Apr;47(4):361-369. doi: 10.1111/imj.13159.

Abstract

Pulmonary hypertension (PH) is a clinical condition characterised by raised pulmonary artery pressure, which results in increased right ventricular afterload and dyspnoea. This is accompanied by reduced exercise capacity, quality of life and, eventually, death. An increasing range of targeted medications has transformed the treatment of pulmonary arterial hypertension, a specific type of PH. Supervised exercise training is recommended as part of a multifaceted management plan for PH. However, many questions remain regarding how exercise training improves exercise capacity and quality of life. The optimal exercise regimen (frequency, timing, duration and intensity) also remains unclear. This review provides an update on the pathophysiology of exercise impairment in PH, suggests mechanisms by which exercise may improve symptoms and function and offers evidence-based recommendations regarding the frequency and intensity of an exercise programme for patients with PH.

Keywords: exercise training; pulmonary hypertension; rehabilitation.

Publication types

  • Review

MeSH terms

  • Evidence-Based Practice
  • Exercise Therapy*
  • Exercise Tolerance / physiology
  • Humans
  • Hypertension, Pulmonary / physiopathology
  • Hypertension, Pulmonary / rehabilitation
  • Hypertension, Pulmonary / therapy*
  • Program Evaluation
  • Quality of Life
  • Treatment Outcome