Development of a French version of the Endometriosis Health Profile 5 (EHP-5): cross-cultural adaptation and psychometric evaluation

Qual Life Res. 2017 Jan;26(1):213-220. doi: 10.1007/s11136-016-1346-y. Epub 2016 Jun 23.

Abstract

Purpose: The Endometriosis Health Profile 5 (EHP-5) is a short version of an endometriosis-specific quality of life questionnaire. The objective of the study was to assess the psychometric validity of its French version.

Methods: A total of 125 patients with histologically proven endometriosis who underwent surgery for painful symptoms and 80 asymptomatic controls completed the EHP-5. Principal components analysis was performed to determine the dimensions of the instrument. Internal consistency was assessed using Cronbach's alpha. Construct validity was assessed by testing the relationship between the EHP-5 and the characteristics of endometriosis.

Results: For each item of EHP-5, endometriosis patients scored significantly higher than control women (p > 0.0001). Eleven items of the EHP-5 were unidimensional with excellent internal consistency (Cronbach's alpha = 0.92), and a summary aggregated index was then constructed. The EHP-5 index was sensitive to the presence of endometriosis, the type, location, severity of the disease, and pain or infertility as the main complaint with effect sizes ranging from 0.48 (95 % CI 0.11-0.85) for superficial endometriosis to 2.56 (95 % CI 2.18-2.93) for deeply infiltrating endometriosis.

Conclusion: The French version of EHP-5 is valid and can be used for reporting patient-orientated outcome in future studies of French-speaking patients with endometriosis.

Keywords: Endometriosis; Pelvic pain; Psychometric validation; Quality of life questionnaire.

MeSH terms

  • Adult
  • Cross-Cultural Comparison*
  • Endometriosis / psychology*
  • Female
  • France
  • Humans
  • Psychometrics / instrumentation*
  • Psychometrics / methods
  • Quality of Life / psychology*
  • Reproducibility of Results
  • Surveys and Questionnaires
  • Translating