Continuous interscalene brachial plexus nerve block prolongs unilateral diaphragmatic dysfunction

Anaesth Crit Care Pain Med. 2016 Dec;35(6):383-390. doi: 10.1016/j.accpm.2016.01.009. Epub 2016 Jun 18.

Abstract

Background and objectives: Single interscalene blocks (ISB) impair pulmonary function (<24h). We hypothesized that continuous ISBs would prolong pulmonary dysfunction until h48 compared with a single ISB. We compared the time course of spirometric and diaphragmatic dysfunction following single or continuous ISBs.

Methods: We prospectively included consecutive adult patients scheduled to undergo shoulder surgery under standard general anaesthesia with single (n=30) or continuous (n=31) ISB. Before ISB (baseline), spirometric tests were recorded and the diaphragm course was evaluated with a B-mode ultrasound technique every 12h until h48. ISBs were performed with 15mL 0.5% ropivacaine using an ultrasound technique approach. The continuous group received the same bolus followed by 0.2% ropivacaine 5mL·h-1 (48h). The primary end point was the reduction (> 25% from baseline) of forced vital capacity (FVC) over the study period (48h).

Results: Patient characteristics were similar in both groups. Thirty minutes after blocks in the PACU, all patients demonstrated a similar and significant unilateral diaphragm paralysis (< 25% from baseline). For the primary end point (FVC), no significant difference was observed between groups over the study period. A difference between single and continuous groups was observed at h24 for: FVC (-25%, P=0.038), FEV1s (-24%, P=0.036), diaphragmatic course (-26%, P=0.02), while no differences for other time points (h0-h48) were noted. Clinical respiratory evaluations (respiratory rate, SpO2, supplementary nasal O2), postoperative pain scores and additional opioid consumption were similar between groups.

Conclusion: Over infusion, continuous ISB did not significantly prolong unilateral phrenic paresis and demonstrated a limited pulmonary impact.

Keywords: Anaesthetic techniques; Anaesthetics techniques; Continuous interscalene; Evaluation; Regional; Spirometry.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Amides
  • Anesthesia Recovery Period
  • Anesthesia, General
  • Anesthetics, Local
  • Brachial Plexus*
  • Diaphragm / diagnostic imaging
  • Diaphragm / physiopathology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Nerve Block / adverse effects*
  • Oxygen / blood
  • Pain, Postoperative / epidemiology
  • Respiratory Function Tests
  • Ropivacaine
  • Shoulder / surgery
  • Spirometry
  • Ultrasonography, Interventional
  • Vital Capacity
  • Young Adult

Substances

  • Amides
  • Anesthetics, Local
  • Ropivacaine
  • Oxygen