Osteoid osteoma mimicking monoarticular juvenile idiopathic arthritis in a girl

Pediatr Int. 2016 Aug;58(8):791-4. doi: 10.1111/ped.12980. Epub 2016 Jun 21.

Abstract

Osteoid osteoma (OO) is a benign osteogenic neoplasm, usually affecting children and young adults, that is typically characterized by nocturnal pain and response to non-steroidal anti-inflammatory drugs. OO is frequently misdiagnosed because it mimics juvenile idiopathic arthritis (JIA), bone infection or malignancy. Herein we report the case of a girl who presented with chronic monoarthritis of the knee mimicking JIA. After 1 year, OO of the femoral distal metaphysis was diagnosed. OO was treated with computed tomography-guided radiofrequency ablation with disappearance of the symptoms and resolution of the neoplasm. No recurrences have been observed 3 years after the treatment. This case highlights that intra-articular or juxta-articular OO should be suspected in the case of misleading symptoms and signs, such as swelling, lack of typical pain and synovial thickening on ultrasound; needle biopsy of the lesion is necessary in the case of confusing imaging.

Keywords: femur; juvenile idiopathic arthritis; needle biopsy; osteoid osteoma; radiofrequency ablation.

Publication types

  • Case Reports

MeSH terms

  • Arthritis, Juvenile / diagnosis*
  • Biopsy, Needle
  • Bone Neoplasms / diagnosis*
  • Bone Neoplasms / surgery
  • Catheter Ablation
  • Child
  • Diagnosis, Differential
  • Female
  • Femur*
  • Humans
  • Knee Joint / diagnostic imaging
  • Magnetic Resonance Imaging
  • Osteoma, Osteoid / diagnosis*
  • Osteoma, Osteoid / surgery
  • Tomography, X-Ray Computed