Synthesis and biomedical applications of aerogels: Possibilities and challenges

Adv Colloid Interface Sci. 2016 Oct:236:1-27. doi: 10.1016/j.cis.2016.05.011. Epub 2016 Jun 8.

Abstract

Aerogels are an exceptional group of nanoporous materials with outstanding physicochemical properties. Due to their unique physical, chemical, and mechanical properties, aerogels are recognized as promising candidates for diverse applications including, thermal insulation, catalysis, environmental cleaning up, chemical sensors, acoustic transducers, energy storage devices, metal casting molds and water repellant coatings. Here, we have provided a comprehensive overview on the synthesis, processing and drying methods of the mostly investigated types of aerogels used in the biological and biomedical contexts, including silica aerogels, silica-polymer composites, polymeric and biopolymer aerogels. In addition, the very recent challenges on these aerogels with regard to their applicability in biomedical field as well as for personalized medicine applications are considered and explained in detail.

Keywords: Aerogels; Biomedical applications; Nanomedicine; Nanoporous materials.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques / instrumentation
  • Biosensing Techniques / methods*
  • Cellulose / chemistry*
  • Diagnostic Imaging / instrumentation
  • Diagnostic Imaging / methods
  • Drug Delivery Systems / instrumentation
  • Drug Delivery Systems / methods
  • Gels
  • Humans
  • Nanomedicine / instrumentation
  • Nanomedicine / methods*
  • Nanostructures / chemistry*
  • Nanostructures / therapeutic use
  • Nanostructures / ultrastructure
  • Phase Transition
  • Porosity
  • Prostheses and Implants
  • Silicon Dioxide / chemistry*
  • Tissue Engineering / instrumentation
  • Tissue Engineering / methods

Substances

  • Gels
  • Silicon Dioxide
  • Cellulose