Impact of Diarrhea on the Clinical Presentation and Outcome of Severe Pneumonia in Bangladeshi Children

Pediatr Infect Dis J. 2016 Oct;35(10):1161-2. doi: 10.1097/INF.0000000000001265.

Abstract

We compared clinical presentation and outcome of 225 children with severe pneumonia between those with and those without diarrhea. Having diarrhea was associated with metabolic acidosis (P < 0.001) and hypocalcemia (P = 0.002) on presentation, and with a fatal outcome: 20/113 (20%) died with diarrhea versus 3/112 (3%) without diarrhea. Diarrhea is an important comorbidity in Bangladeshi children with severe pneumonia requiring attention for improved case management.

Publication types

  • Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acidosis
  • Bangladesh / epidemiology
  • Case-Control Studies
  • Child, Preschool
  • Diarrhea / complications*
  • Diarrhea / epidemiology
  • Diarrhea / mortality*
  • Humans
  • Infant
  • Infant, Newborn
  • Pneumonia / complications*
  • Pneumonia / epidemiology
  • Pneumonia / mortality*
  • Risk Factors
  • Treatment Outcome