Ultrasound in the diagnosis of asymptomatic hyperuricaemia and gout

Rev Clin Esp (Barc). 2016 Nov;216(8):445-450. doi: 10.1016/j.rce.2016.05.007. Epub 2016 Jun 6.
[Article in English, Spanish]

Abstract

The increase in serum urate concentrations (hyperuricaemia, ≥7.0mg/dL) creates crystals, which promote inflammation and joint lesions. Ultrasonography can reveal these urate deposits. The presence of crystals suggests that a patient with hyperuricaemia is actually experiencing asymptomatic gout, and that a patient with gout without subcutaneous tophi could experience tophaceous gout. The information offered by ultrasound (double contour sign and hyperechoic concretions mimicking clouds) enables a more specific classification of hyperuricaemia and gout. Additionally, this information can lead to relevant changes in terms of the diagnosis and therapeutic approach for patients with hyperuricaemia and gout.

Keywords: Double contour sign; Gota; Gout; Hiperuricemia; Hyperuricaemia; Signo del doble contorno; Tofos; Tophi.