What is the evidence for stress resistance and slowed aging?

Karyn L Hamilton; Benjamin F Miller

doi:10.1016/j.exger.2016.06.001

What is the evidence for stress resistance and slowed aging?

Exp Gerontol. 2016 Sep:82:67-72. doi: 10.1016/j.exger.2016.06.001. Epub 2016 Jun 4.

Authors

Karyn L Hamilton¹, Benjamin F Miller²

Affiliations

¹ Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, United States. Electronic address: Karyn.hamilton@colostate.edu.
² Department of Health and Exercise Science, Colorado State University, Fort Collins, CO, United States.

PMID: 27268049
DOI: 10.1016/j.exger.2016.06.001

Abstract

Stress resistance is thought to contribute to slowed-aging, although cause and effect between the two is controversial. On October 30, 2015 researchers gathered at the Front Range Consortium on Stress Resistance and Slowed Aging in Fort Collins, CO, to discuss what the current evidence is that stress resistance imparts slowed aging. Included in that discussion was defining stress resistance, distinguishing if there are key stresses to which resistance imparts slowed aging, what models aid in our understanding of stress resistance and aging, and how to translate that knowledge into slowed aging treatment. The following article is a brief summary of that discussion and recommendations for moving forward.

Keywords: Aging; Healthspan; Hormesis; Longevity; Resilience; Slowed Aging; Stress.

Publication types

Review
Research Support, Non-U.S. Gov't

MeSH terms

Aging / physiology*
Animals
Congresses as Topic
Humans
Stress, Physiological*