Pathogen-associated molecular patterns (PAMPs) are conservative molecules associated with groups of pathogens or their products. These molecules are recognized by relevant receptors. PAMPs induce the expression of inflammatory cytokines through the signal cascade. The role of PAMPs in the initiation and development of periodontitis is recently attracting attention. PAMPs induce the expression of inflammatory mediators after they are recognized in the periodontium. This process damages the periodontal soft tissue and osseous tissue, thus resulting in periodontitis. The results of this study will provide an excellent resolution for the treatment of periodontitis by blocking the pathogenic pathway of PAMPs.
病原体相关分子模式（PAMPs）是一类存在于病原体及其产物中的结构保守的分子。它能被相关受体识别，并通过信号级联反应诱导炎症因子的表达。近年来，PAMPs在牙周炎起始及发展中的作用逐渐得到关注。PAMPs在牙周被识别后，进而诱导组织表达炎症因子对牙周软组织及骨组织进行破坏，引发牙周炎。阻断PAMPs致病途径可能为牙周炎的治疗提供新的思路。