Primary Musculoskeletal Lymphoma

Radiol Clin North Am. 2016 Jul;54(4):785-95. doi: 10.1016/j.rcl.2016.03.008.

Abstract

Primary lymphoma of bone and soft tissue is rare and almost invariably of B-cell origin. Osseous lymphoma usually reveals aggressive bone destruction and associated soft tissue extension. Soft tissue involvement is optimally depicted by MR imaging. Cortical destruction allowing communication between the intraosseous and soft tissue components may be subtle with small striations of extension. Lymphoma of the deep soft tissues usually reveals long cones of intramuscular or intermuscular tumor again best depicted by MR imaging. Cutaneous or subcutaneous lymphoma demonstrates multiple nodules and plaquelike thickening.

Keywords: B-cell lymphoma; Extranodal lymphoma; Primary bone lymphoma; Primary soft tissue lymphoma.

Publication types

  • Review

MeSH terms

  • Bone Neoplasms / diagnostic imaging*
  • Bone Neoplasms / pathology*
  • Diagnosis, Differential
  • Evidence-Based Medicine
  • Humans
  • Lymphoma / diagnostic imaging*
  • Lymphoma / pathology*
  • Magnetic Resonance Imaging / methods
  • Muscle Neoplasms / diagnostic imaging*
  • Muscle Neoplasms / pathology*
  • Positron-Emission Tomography / methods
  • Tomography, X-Ray Computed / methods