Anti-Toxoplasma antibodies prevalence and associated risk factors among HIV patients

Dechassa Tegegne; Mukarim Abdurahaman; Tadesse Mosissa; Moti Yohannes

doi:10.1016/j.apjtm.2016.03.034

Anti-Toxoplasma antibodies prevalence and associated risk factors among HIV patients

Asian Pac J Trop Med. 2016 May;9(5):460-4. doi: 10.1016/j.apjtm.2016.03.034. Epub 2016 Mar 23.

Authors

Dechassa Tegegne¹, Mukarim Abdurahaman², Tadesse Mosissa³, Moti Yohannes²

Affiliations

¹ Department of Microbiology and Veterinary Public Health, Jimma University, P.O. Box 307, Jimma, Ethiopia. Electronic address: dachassat@yahoo.com.
² Department of Microbiology and Veterinary Public Health, Jimma University, P.O. Box 307, Jimma, Ethiopia.
³ Department of Natural Resource Management, Jimma University, P.O. Box 307, Jimma, Ethiopia.

PMID: 27261854
DOI: 10.1016/j.apjtm.2016.03.034

Abstract

Objectives: To assess the seroprevalence and associated risk factors of toxoplasmosis among HIV patients in Agaro Town Health Center of Jimma zone.

Methods: Convenient sampling was used to collect blood samples from 135 patients attending anti-retroviral therapy from February to March 2015. Serum samples were tested for anti-Toxoplasma gondii (T. gondii) antibody by using latex agglutination test. Structured questionnaire was used to collect data on socio-demographic and risk factors associated with toxoplasmosis.

Results: Overall seroprevalence of toxoplasmosis was 80.7% (109/135, CI: 74.04-87.36). In multivariate analysis significant association was observed between anti-T. gondii seropositivity and raw meat consumption (OR: 3.514, CI: 1.167-10.581, P = 0.025), knowledge about toxoplasmosis (OR: 5.225, CI: 1.382, P = 0.015) and sex (OR: 4.023, CI: 1.382-19.762, P = 0.015).

Conclusions: Immuno compromised patients showed high rate of seropositivity and thus, it is highly advisable to introduce routine anti-T. gondii antibodies serological screening test prior to ART commencement.

Keywords: HIV; LAT; Seroprevalence; Toxoplasma gondii.