Sorbicillinoids from Fungi and Their Bioactivities

Molecules. 2016 Jun 1;21(6):715. doi: 10.3390/molecules21060715.

Abstract

Sorbicillinoids are important hexaketide metabolites derived from fungi. They have a variety of biological activities including cytotoxic, antioxidant, antiviral and antimicrobial activity. The unique structural features of the sorbicillinoids make them attractive candidates for developing new pharmaceutical and agrochemical agents. About 90 sorbicillinoids have been reported in the past few decades. This mini-review aims to briefly summarize their occurrence, structures, and biological activities.

Keywords: biological activities; bisorbicillinoids; fungi; occurrence; sorbicillin; sorbicillinoids; trisorbicillinoids; vertinoids.

Publication types

  • Review

MeSH terms

  • Anti-Infective Agents / chemistry
  • Anti-Infective Agents / pharmacology
  • Antineoplastic Agents / chemistry
  • Antineoplastic Agents / pharmacology
  • Antioxidants / chemistry
  • Antioxidants / pharmacology
  • Biological Products / chemistry*
  • Biological Products / isolation & purification
  • Biological Products / pharmacology*
  • Cell Survival / drug effects
  • Cyclohexanones / chemistry*
  • Cyclohexanones / isolation & purification
  • Cyclohexanones / pharmacology*
  • Fungi / chemistry*
  • Humans
  • Molecular Structure

Substances

  • Anti-Infective Agents
  • Antineoplastic Agents
  • Antioxidants
  • Biological Products
  • Cyclohexanones
  • sorbicillinol