Endovascular retrograde recanalization in Asian critical limb ischaemia patients

ANZ J Surg. 2017 Sep;87(9):E61-E64. doi: 10.1111/ans.13649. Epub 2016 Jun 3.

Abstract

Background: To evaluate endovascular retrograde recanalization of critical limb ischaemia (CLI) patients with chronic total occlusions (CTOs) in an Asian population.

Methods: We conducted a single centre-based retrospective review of CLI patients with CTOs who had undergone endovascular retrograde recanalization using the subintimal arterial flossing with antegrade-retrograde intervention technique.

Results: A total of 40 CLI patients with CTOs underwent endovascular intervention. The median age was 71 years; 67.5% were males and Chinese accounted for 65% of the patients, of which 55% were in Rutherford category 6, 37.5% in category 5 and 7.5% in category 4. Antegrade-retrograde access was performed via the femoral artery in 39 cases and the brachial artery in one case for the proximal puncture, and the following arteries for the distal puncture: superficial femoral, n = 4 (10%); popliteal, n = 4 (10%); anterior tibial, n = 12 (30%); dorsalis pedis, n = 9 (22.5%); peroneal, n = 4 (10%) and posterior tibial, n = 7 (17.5%). Technical success was high at 92.5% (n = 37). After intervention, 25% (n = 10) had below-knee triple vessel runoff, 52.5% (n = 21) had double vessel runoff and 15.0% (n = 6) had single vessel runoff. Stenting for target vessel dissections was required in 12 patients. There were two cases of significant bleeding; one common femoral artery pseudoaneurysm was treated with ultrasound-guided thrombin injection and another case of distal puncture site bleeding only required compression. Limb salvage at 1 year was 92.5% (n = 37).

Conclusion: The subintimal arterial flossing with antegrade-retrograde intervention technique is safe with high technical success rates and acceptable outcomes in Asian CLI patients with CTOs.

Keywords: SAFARI; critical limb ischaemia; endovascular; retrograde recanalization.

MeSH terms

  • Aged
  • Aged, 80 and over
  • Angioplasty, Balloon / methods
  • Arterial Occlusive Diseases / therapy*
  • Asian People / ethnology*
  • Endovascular Procedures / methods*
  • Extremities / blood supply*
  • Extremities / pathology
  • Female
  • Humans
  • Ischemia / etiology
  • Ischemia / surgery*
  • Limb Salvage / methods*
  • Male
  • Middle Aged
  • Peripheral Arterial Disease / complications
  • Peripheral Arterial Disease / pathology
  • Punctures / statistics & numerical data
  • Retrospective Studies
  • Stents / statistics & numerical data
  • Treatment Outcome
  • Ultrasonography, Interventional / instrumentation