Five cases of cysticercosis are reported. They were diagnosed by microscopic examination of the sub-cutaneous nodules in which T. Solium larvae were found. Results of the treatment by Praziquantel are reported, with regard to the symptomatology of the patients after one year of observation. Necrosis of cysticerci larvae few month after starting the treatment was observed in three cases by microscopical anatomy test. Three doses of Praziquantel of 20 mg/kg at four hours of interval are efficient against sub-cutaneous and muscular cysticercosis. Such a treatment presents the advantage very important in some rural zones in Africa, of a single dose in one day.