Aspergillosis of the Heart and Lung and Review of Published Reports on Fungal Endocarditis

Mycopathologia. 2016 Aug;181(7-8):583-8. doi: 10.1007/s11046-016-0012-9. Epub 2016 May 31.

Abstract

Invasive aspergillosis (IA) is increasingly diagnosed in high-risk patients. The lesions are usually located in the lungs and/or sinuses, and the fungus may spread haematogenously to different organs; however, involvement of the heart during IA is very rare. We describe a unique case of invasive aspergillosis of the heart septum and the lungs in the allogeneic haematopoietic stem cell transplant recipient.

Keywords: Amphotericin B; Heart; Invasive aspergillosis; Lung; Stem cell transplantation.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Aspergillus / isolation & purification*
  • Endocarditis / etiology*
  • Endocarditis / pathology*
  • Hematopoietic Stem Cell Transplantation / adverse effects
  • Histocytochemistry
  • Humans
  • Immunocompromised Host
  • Invasive Pulmonary Aspergillosis / complications*
  • Invasive Pulmonary Aspergillosis / diagnosis*
  • Invasive Pulmonary Aspergillosis / microbiology
  • Invasive Pulmonary Aspergillosis / pathology
  • Lung / microbiology
  • Lung / pathology
  • Male
  • Microscopy
  • Middle Aged
  • Myocardium / pathology
  • Transplantation, Homologous / adverse effects