Patterned and Specific Attachment of Bacteria on Biohybrid Bacteria-Driven Microswimmers

Ajay Vikram Singh; Metin Sitti

doi:10.1002/adhm.201600155

Patterned and Specific Attachment of Bacteria on Biohybrid Bacteria-Driven Microswimmers

Adv Healthc Mater. 2016 Sep;5(18):2325-31. doi: 10.1002/adhm.201600155. Epub 2016 May 30.

Authors

Ajay Vikram Singh¹, Metin Sitti²

Affiliations

¹ Physical Intelligence Department, Max Planck Institute for Intelligent Systems, Heisenbergstr. 3, 70569, Stuttgart, Germany.
² Physical Intelligence Department, Max Planck Institute for Intelligent Systems, Heisenbergstr. 3, 70569, Stuttgart, Germany. sitti@is.mpg.de.

PMID: 27240122
DOI: 10.1002/adhm.201600155

Abstract

A surface patterning technique and a specific and strong biotin-streptavidin bonding of bacteria on patterned surfaces are proposed to fabricate Janus particles that are propelled by the attached bacteria. Bacteria-driven Janus microswimmers with diameters larger than 3 μm show enhanced mean propulsion speed. Such microswimmers could be used for future applications such as targeted drug delivery and environmental remediation.

Keywords: E. coli; Janus; active matter; biohybrid; microswimmer.

MeSH terms

Bacterial Adhesion*
Drug Delivery Systems / methods
Environmental Restoration and Remediation / methods
Locomotion*
Serratia marcescens*