DsRNA disrupts airway epithelial barrier integrity through down-regulation of claudin members

Allergol Int. 2016 Sep:65 Suppl:S56-8. doi: 10.1016/j.alit.2016.04.006. Epub 2016 May 26.

Authors

Yasuhiro Gon¹, Shuichiro Maruoka², Hiroyuki Kishi³, Yutaka Kozu¹, Kazumichi Kuroda⁴, Kenji Mizumura¹, Yasuyuki Nomura³, Takeshi Oshima³, Shu Hashimoto¹

Affiliations

¹ Division of Respiratory Medicine, Nihon University School of Medicine, Tokyo, Japan.
² Division of Respiratory Medicine, Nihon University School of Medicine, Tokyo, Japan. Electronic address: maruoka.shuichiro@nihon-u.ac.jp.
³ Division of Otolaryngology, Nihon University School of Medicine, Tokyo, Japan.
⁴ Division of Microbiology, Nihon University School of Medicine, Tokyo, Japan.

PMID: 27238378
DOI: 10.1016/j.alit.2016.04.006

No abstract available

Publication types

Letter

MeSH terms

Cell Line
Claudins / genetics*
Down-Regulation
Epithelial Cells
Gene Expression Regulation*
Humans
RNA Interference
RNA Viruses / physiology
RNA, Double-Stranded / genetics*
RNA, Small Interfering / genetics
Respiratory Mucosa / metabolism*
Respiratory Mucosa / pathology*
Respiratory Mucosa / virology

Substances

Claudins
RNA, Double-Stranded
RNA, Small Interfering