Background: Liposclerosing myxofibrous primary bone tumor is a rare benign bone lesion that was characterized by complex mixture of various histological elements.
Methods: We have studied the radiological, clinical and pathological features of nine patients with this disorder. Pain and limping were the main symptoms.
Results: Radiographic images typically showed a geographic lytic lesion with thick sclerotic margin, reflecting a pattern of slow growth. Histological sections revealed a polymorphic neoplasia characterized by predominant proliferation of stellate and fusiform cells aimed the myxoid matrix.
Conclusions: These features suggest that the lesion may represent a variant of fibrous dysplasia with a high risk of malignant transformation.
Keywords: Bone tumors; Liposclerosing myxofibrous tumor; Series of cases.