Update on advances in molecular PET in urological oncology

Jpn J Radiol. 2016 Jul;34(7):470-85. doi: 10.1007/s11604-016-0553-3. Epub 2016 May 24.

Abstract

Integrated positron emission tomography/computed tomography (PET/CT) with 2-[(18)F]fluoro-2-deoxy-D-glucose ((18)F-FDG) has emerged as a powerful tool for the combined metabolic and anatomic evaluation of many cancers. In urological oncology, however, the use of (18)F-FDG has been limited by a generally low tumor uptake, and physiological excretion of FDG through the urinary system. (18)F-FDG PET/CT is useful when applied to specific indications in selected patients with urological malignancy. New radiotracers and positron emission tomography/magnetic resonance imaging (PET/MRI) are expected to further improve the performance of PET in uro-oncology.

Keywords: Bladder cancer; Kidney cancer; Positron emission tomography/computed tomography (PET/CT); Positron emission tomography/magnetic resonance imaging (PET/MRI); Prostate cancer; Testicular cancer; Urological cancer.

Publication types

  • Review

MeSH terms

  • Female
  • Fluorodeoxyglucose F18*
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Multimodal Imaging / methods
  • Positron Emission Tomography Computed Tomography
  • Positron-Emission Tomography / methods*
  • Radiopharmaceuticals*
  • Urinary Tract / diagnostic imaging
  • Urologic Neoplasms / diagnostic imaging*

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18