What's Hot in Schizophrenia Research?

Psychiatr Clin North Am. 2016 Jun;39(2):343-51. doi: 10.1016/j.psc.2016.01.011. Epub 2016 Mar 2.

Abstract

Schizophrenia is a heterogeneous psychiatric illness for which the cause or causes are presently unknown. There is increasing evidence from multiple levels of research suggesting that inflammation may play an important role in the development and persistence of psychosis and cognitive impairment in a proportion of people with schizophrenia. This overview of recent literature focuses on studies of neuroinflammation that are considered to be of increasing interest in schizophrenia research and are poised to have an impact on the cause, diagnosis, and potential treatment of at least some forms or subtypes of schizophrenia.

Keywords: Biomarkers; Cytokines; Inflammation; Microglia; Psychosis; Schizophrenia; Ultra-high risk.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Autopsy
  • Biomarkers / metabolism
  • Genome-Wide Association Study
  • Humans
  • Inflammation / complications
  • Inflammation / genetics
  • Inflammation / metabolism
  • Neuroimaging / methods
  • Research / trends*
  • Schizophrenia / etiology*
  • Schizophrenia / genetics
  • Schizophrenia / pathology*

Substances

  • Biomarkers