A feasibility study for producing an egg matrix candidate reference material for the polyether ionophore salinomycin

Talanta. 2016 Aug 1:155:222-8. doi: 10.1016/j.talanta.2016.04.025. Epub 2016 Apr 12.

Abstract

The aim of this work was to study the feasibility of producing an egg matrix candidate reference material for salinomycin. Preservation techniques investigated were freeze-drying and spray drying dehydration. Homogeneity and stability studies of the produced batches were conducted according to ISO Guides 34 and 35. The results showed that all produced batches were homogeneous and both freeze-drying and spray drying techniques were suitable for matrix dehydrating, ensuring the material stability. In order to preserve the material integrity, it must be transported within the temperature range of -20 up to 25°C. The results constitute an important step towards the development of an egg matrix reference material for salinomycin is possible.

Keywords: Coccidiostats; Egg; Polyether ionophore; Reference materials; Salinomycin; Veterinary drug residues.

MeSH terms

  • Accreditation
  • Agriculture / standards*
  • Animals
  • Chickens
  • Eggs*
  • Ether / chemistry*
  • Feasibility Studies
  • Freeze Drying
  • Ionophores / chemistry*
  • Ionophores / pharmacology
  • Pyrans / chemistry*
  • Pyrans / pharmacology
  • Reference Standards

Substances

  • Ionophores
  • Pyrans
  • Ether
  • salinomycin