Plasmablastic Richter transformation as a resistance mechanism for chronic lymphocytic leukaemia treated with BCR signalling inhibitors

Br J Haematol. 2017 Apr;177(2):324-328. doi: 10.1111/bjh.14062. Epub 2016 May 15.

Authors

Kah-Lok Chan¹, Piers Blombery¹, Kate Jones¹, Stephen Lade², Dennis Carney¹, Huy Tran³, John F Seymour^{1

4}, Constantine S Tam^{1

4}

Affiliations

¹ Department of Haematology, Peter MacCallum Cancer Centre, Victoria, Australia.
² Department of Anatomical Pathology, Peter MacCallum Cancer Centre, Victoria, Australia.
³ Department of Haematology, Frankston Hospital, Victoria, Australia.
⁴ The University of Melbourne, Victoria, Australia.

PMID: 27196127
DOI: 10.1111/bjh.14062

No abstract available

Keywords: B-cell receptor signalling inhibitors; Chronic lymphocytic leukaemia; ibrutinib; plasmablastic lymphoma; richter transformation.

Publication types

Letter
Comment

MeSH terms

Humans
Leukemia, Lymphocytic, Chronic, B-Cell*
Lymphoma, Large B-Cell, Diffuse*
Plasma Cells