Fe-Catalyzed Hydroalkylation of Olefins with para-Quinone Methides

Org Lett. 2016 Jun 3;18(11):2722-5. doi: 10.1021/acs.orglett.6b01173. Epub 2016 May 18.

Abstract

A novel Fe-catalyzed hydroalkylation of olefins with para-quinone methides (p-QMs) for accessing phenols has been developed. In this protocol, various olefins could convert to alkyl radicals and undergo addition to para-quinone methides toward C-C bond formation and aromatization. The reaction conditions are mild and the substrate scopes are broad.

Publication types

  • Research Support, Non-U.S. Gov't