Accidental hypothermia in severe trauma

Anaesth Crit Care Pain Med. 2016 Oct;35(5):355-361. doi: 10.1016/j.accpm.2016.05.001. Epub 2016 May 13.

Abstract

Hypothermia, along with acidosis and coagulopathy, is part of the lethal triad that worsen the prognosis of severe trauma patients. While accidental hypothermia is easy to identify by a simple measurement, it is no less pernicious if it is not detected or treated in the initial phase of patient care. It is a multifactorial process and is a factor of mortality in severe trauma cases. The consequences of hypothermia are many: it modifies myocardial contractions and may induce arrhythmias; it contributes to trauma-induced coagulopathy; from an immunological point of view, it diminishes inflammatory response and increases the chance of pneumonia in the patient; it inhibits the elimination of anaesthetic drugs and can complicate the calculation of dosing requirements; and it leads to an over-estimation of coagulation factor activities. This review will detail the pathophysiological consequences of hypothermia, as well as the most recent principle recommendations in dealing with it.

Keywords: Coagulopathy; Haemostasis; Hypothermia; Mortality; Polytrauma.

Publication types

  • Review

MeSH terms

  • Acidosis / etiology
  • Acidosis / mortality
  • Blood Coagulation Disorders / etiology
  • Blood Coagulation Disorders / mortality
  • Humans
  • Hypothermia / etiology*
  • Hypothermia / mortality
  • Hypothermia / therapy*
  • Prognosis
  • Wounds and Injuries / complications*
  • Wounds and Injuries / mortality