Iatrogenic Bladder Injury: National Analysis of 30-Day Outcomes

Urology. 2016 Nov:97:250-256. doi: 10.1016/j.urology.2016.05.002. Epub 2016 May 12.

Abstract

Objective: To examine the risk factors and outcomes of BI, a rare complication of abdominopelvic surgery.

Methods: We queried the National Surgical Quality Improvement Program database to identify intraoperative bladder injury (BI) defined by the Current Procedural Terminology code for cystorrhaphy from 2005 to 2013. Propensity-score matching balanced the differences between patients with BI and the controls. The factors matched included age, body mass index, race, modified frailty index, and procedure category.

Results: There were 1685 cases of BI in 1,541,736 surgeries (0.11%). Although 49.5% of surgeries were performed in an open fashion, this approach accounted for 69.3% of BI (P < .001). Prior to matching, mortality rates and morbidity were increased for the BI group (P < .001). Moreover, age, recent chemotherapy or radiation or steroid history, and smoking were among the risk factors for BI (all P < .05). Resident involvement increased the odds of BI and complications after BI, but decreased the risk of readmission (all P < .05). After matching, 30-day mortality was no longer increased for patients with BI (P < .001). Patients with BI requiring repair did have increased median length of stay (6 days [interquartile range {IQR}: 3-11] vs 5 [IQR: 2-9]; P < .001) and operative time (203 min [IQR: 140-278] vs 134 [IQR: 86-199]; P < .001). BI patients were more likely to undergo reoperation (7.7% vs 5.3%; P = .005). Urine infection, sepsis, and bleeding were more likely in the BI group compared with the matched controls (all P < .001). Delayed repair was rare.

Conclusion: We present the largest national series assessing iatrogenic BI and subsequent repair. BI increases 30-day complications, reoperation, and length of stay but does not increase 30-day mortality compared with matched controls. More complex surgical cases and increased baseline comorbidity were risk factors for BI.

MeSH terms

  • Abdomen / surgery
  • Age Factors
  • Antineoplastic Agents / therapeutic use
  • Clinical Competence
  • Hemorrhage / epidemiology
  • Hemorrhage / etiology
  • Humans
  • Iatrogenic Disease / epidemiology
  • Internship and Residency
  • Intraoperative Complications / epidemiology*
  • Intraoperative Complications / surgery
  • Length of Stay / statistics & numerical data
  • Mortality
  • Operative Time
  • Patient Readmission / statistics & numerical data*
  • Pelvis / surgery
  • Postoperative Complications / epidemiology
  • Radiotherapy
  • Reoperation / statistics & numerical data*
  • Risk Factors
  • Sepsis / epidemiology
  • Sepsis / etiology
  • Smoking / epidemiology
  • Steroids / therapeutic use
  • Surgical Wound / complications
  • Surgical Wound / epidemiology*
  • Surgical Wound / surgery
  • United States / epidemiology
  • Urinary Bladder / injuries*
  • Urinary Tract Infections / epidemiology
  • Urinary Tract Infections / etiology

Substances

  • Antineoplastic Agents
  • Steroids