Biodegradable/biocompatible coated metal implants for orthopedic applications

Biomed Mater Eng. 2016 May 12;27(1):87-99. doi: 10.3233/BME-161568.

Abstract

Biocompatible metals have been suggested as revolutionary biomaterials for bone-grafting therapies. Although metals and their alloys are widely and successfully used in producing biomedical implants due to their good mechanical properties and corrosion resistance, they have a lack in bioactivity. Therefore coating of the metal surface with calcium phosphates (CaP) is a benign way to achieve well bioactivity and get controlled corrosion properties. The biocompatibility and bioactivity calcium phosphates (CaP) in bone growth were guided them to biomedical treatment of bone defects and fractures. Many techniques have been used for fabrication of CaP coatings on metal substrates such as magnesium and titanium. The present review will focus on the synthesis of CaP and their relative forms using different techniques especially electrochemical techniques. The latter has always been known of its unique way of optimizing the process parameters that led to a control in the structure and characteristics of the produced materials.

Keywords: Calcium phosphate; biodegradable; biomaterial; composite; scaffold.

Publication types

  • Review

MeSH terms

  • Animals
  • Biomimetics / methods
  • Bone Substitutes / chemical synthesis
  • Bone Substitutes / chemistry*
  • Calcium Phosphates / chemical synthesis
  • Calcium Phosphates / chemistry*
  • Coated Materials, Biocompatible / chemical synthesis
  • Coated Materials, Biocompatible / chemistry*
  • Electrochemical Techniques / methods
  • Humans
  • Magnesium / chemistry
  • Metals / chemical synthesis
  • Metals / chemistry*
  • Orthopedics / methods
  • Prostheses and Implants
  • Surface Properties

Substances

  • Bone Substitutes
  • Calcium Phosphates
  • Coated Materials, Biocompatible
  • Metals
  • Magnesium