Restriction of Zika Virus by Host Innate Immunity

Xuping Xie; Chao Shan; Pei-Yong Shi

doi:10.1016/j.chom.2016.04.019

Restriction of Zika Virus by Host Innate Immunity

Cell Host Microbe. 2016 May 11;19(5):566-7. doi: 10.1016/j.chom.2016.04.019.

Authors

Xuping Xie¹, Chao Shan¹, Pei-Yong Shi²

Affiliations

¹ Departments of Biochemistry & Molecular Biology and Pharmacology & Toxicology, and Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA.
² Departments of Biochemistry & Molecular Biology and Pharmacology & Toxicology, and Sealy Center for Structural Biology & Molecular Biophysics, University of Texas Medical Branch, Galveston, TX 77555, USA. Electronic address: peshi@utmb.edu.

PMID: 27173920
DOI: 10.1016/j.chom.2016.04.019

Abstract

Recent epidemics of Zika virus (ZIKV) have brought increasing concerns of heightened disease severity and neurotropism. In this issue of Cell Host & Microbe, Lazear et al. (2016) and Bayer et al. (2016) show that innate immunity can restrict ZIKV infection and disease development.

Publication types

Comment

MeSH terms

Aedes / virology
Insect Vectors / virology
RNA, Viral
Zika Virus Infection*
Zika Virus*

Substances

RNA, Viral