The Homocoupling Reaction of Aromatic Terminal Alkynes by a Highly Active Palladium(II)/AgNO₃ Cocatalyst in Aqueous Media Under Aerobic Conditions

Mengping Guo; Bo Chen; Meiyun Lv; Xiuling Zhou; Yongju Wen; Xiuli Shen

doi:10.3390/molecules21050606

The Homocoupling Reaction of Aromatic Terminal Alkynes by a Highly Active Palladium(II)/AgNO₃ Cocatalyst in Aqueous Media Under Aerobic Conditions

Molecules. 2016 May 10;21(5):606. doi: 10.3390/molecules21050606.

Authors

Mengping Guo^{1

2}, Bo Chen^{3

4}, Meiyun Lv⁵, Xiuling Zhou⁶, Yongju Wen⁷, Xiuli Shen⁸

Affiliations

¹ Institue of Coordination Catalysis, College of Chemistry and Bio-Engineering, Yichun University, Yichun 336000, China. guomengping65@163.com.
² Engineering Center of Jiangxi University for Lithium Energy, Yichun University, Yichun 336000, China. guomengping65@163.com.
³ Institue of Coordination Catalysis, College of Chemistry and Bio-Engineering, Yichun University, Yichun 336000, China. chenbo25719@163.com.
⁴ Engineering Center of Jiangxi University for Lithium Energy, Yichun University, Yichun 336000, China. chenbo25719@163.com.
⁵ Institue of Coordination Catalysis, College of Chemistry and Bio-Engineering, Yichun University, Yichun 336000, China. lvmeiyun2005@163.com.
⁶ Institue of Coordination Catalysis, College of Chemistry and Bio-Engineering, Yichun University, Yichun 336000, China. 13879593114@163.com.
⁷ Institue of Coordination Catalysis, College of Chemistry and Bio-Engineering, Yichun University, Yichun 336000, China. wenyongjujuju@163.com.
⁸ Institue of Coordination Catalysis, College of Chemistry and Bio-Engineering, Yichun University, Yichun 336000, China. shenxiuliwyj@163.com.

Abstract

A new and efficient Pd(II)/AgNO₃-cocatalyzed homocoupling of aromatic terminal alkynes is described. Various symmetrical 1,4-disubstituted-1,3-diynes are obtained in good to excellent yields. This protocol employs a loading with relatively low palladium(II) in aqueous media under aerobic conditions.

Keywords: aromatic terminal alkynes; homocoupling reaction; palladium(II)/AgNO3 cocatalyzing.

MeSH terms

Alkynes / chemical synthesis*
Alkynes / chemistry
Catalysis
Molecular Structure
Palladium / chemistry*
Silver Nitrate / chemistry*
Water

Substances

Alkynes
Water
Palladium
Silver Nitrate