Influence of age and gender on the profile of exhaled volatile organic compounds analyzed by an electronic nose

J Bras Pneumol. 2016 Apr;42(2):143-5. doi: 10.1590/S1806-37562015000000195.
[Article in English, Portuguese]

Abstract

We aimed to investigate the effects of age and gender on the profile of exhaled volatile organic compounds. We evaluated 68 healthy adult never-smokers, comparing them by age and by gender. Exhaled breath samples were analyzed by an electronic nose (e-nose), resulting in "breathprints". Principal component analysis and canonical discriminant analysis showed that older subjects (≥ 50 years of age) could not be distinguished from younger subjects on the basis of their breathprints, as well as that the breathprints of males could not distinguished from those of females (cross-validated accuracy, 60.3% and 57.4%, respectively).Therefore, age and gender do not seem to affect the overall profile of exhaled volatile organic compounds measured by an e-nose.

Objetivamos investigar os efeitos da idade e do gênero no perfil de compostos orgânicos voláteis exalados. Avaliamos 68 adultos saudáveis nunca fumantes, comparando-os pela idade e gênero. Analisamos amostras de ar exalado por um nariz eletrônico, o que resultou em "breathprints". A análise dos principais componentes e a análise discriminante canônica mostraram que não houve distinção dos breathprints entre indivíduos mais velhos (≥ 50 anos) e mais jovens e nem entre homens e mulheres (acurácia com validação cruzada de 60,3% e 57,4%, respectivamente). Portanto, idade e gênero parecem não afetar o perfil global de compostos orgânicos voláteis exalados medidos por nariz eletrônico.

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Analysis of Variance
  • Breath Tests / methods
  • Cross-Sectional Studies
  • Electronic Nose*
  • Exhalation*
  • Female
  • Healthy Volunteers
  • Humans
  • Male
  • Middle Aged
  • Reference Values
  • Sex Factors
  • Spirometry
  • Volatile Organic Compounds / analysis*
  • Young Adult

Substances

  • Volatile Organic Compounds