BrucellaBase: Genome information resource

Infect Genet Evol. 2016 Sep:43:38-42. doi: 10.1016/j.meegid.2016.05.006. Epub 2016 May 7.

Abstract

Brucella sp. causes a major zoonotic disease, brucellosis. Brucella belongs to the family Brucellaceae under the order Rhizobiales of Alphaproteobacteria. We present BrucellaBase, a web-based platform, providing features of a genome database together with unique analysis tools. We have developed a web version of the multilocus sequence typing (MLST) (Whatmore et al., 2007) and phylogenetic analysis of Brucella spp. BrucellaBase currently contains genome data of 510 Brucella strains along with the user interfaces for BLAST, VFDB, CARD, pairwise genome alignment and MLST typing. Availability of these tools will enable the researchers interested in Brucella to get meaningful information from Brucella genome sequences. BrucellaBase will regularly be updated with new genome sequences, new features along with improvements in genome annotations. BrucellaBase is available online at http://www.dbtbrucellosis.in/brucellabase.html or http://59.99.226.203/brucellabase/homepage.html.

Keywords: BLAST; BrucellaBase; CARD; MLST; Phylogeny; VFDB.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Typing Techniques / methods*
  • Base Sequence
  • Brucella / genetics*
  • Databases, Genetic
  • Genome, Bacterial*
  • Internet
  • Multilocus Sequence Typing / methods*
  • Phylogeny
  • Species Specificity