Specific gene polymorphisms are known to be associated with a different arterial physiology in the younger generation. The present study found that young Russians with the matrix metalloproteinase 3 6A/6A and γ-glutamyltransferase 1AA genotypes have lower levels of the cardio-ankle vascular index - a recent measure of arterial stiffness. This observation may serve as an additional tool for cardiovascular disease prevention in the young population.
Keywords: Arterial stiffness; cardio-ankle vascular index; matrix metalloproteinase; polymorphism; stromelysin-1; γ-glutamyltransferase.