PET Imaging of Pheochromocytoma

Sameer Khan; Zarni Win; Teresa Szyszko; Claire Lloyd; Joel Dunn; Abass Alavi; Adil Al-Nahhas

doi:10.1016/j.cpet.2008.04.003

PET Imaging of Pheochromocytoma

PET Clin. 2007 Jul;2(3):341-9. doi: 10.1016/j.cpet.2008.04.003. Epub 2008 Sep 19.

Authors

Sameer Khan¹, Zarni Win¹, Teresa Szyszko¹, Claire Lloyd¹, Joel Dunn¹, Abass Alavi², Adil Al-Nahhas³

Affiliations

¹ Departments of Nuclear Medicine and Imaging, Imperial College Healthcare Trust, Du Cane Road, London W12 0HS, United Kingdom.
² Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA 19104, USA.
³ Departments of Nuclear Medicine and Imaging, Imperial College Healthcare Trust, Du Cane Road, London W12 0HS, United Kingdom. Electronic address: adil.al-nahhas@imperial.nhs.uk.

PMID: 27158015
DOI: 10.1016/j.cpet.2008.04.003

Abstract

Pheochromocytomas are tumors derived from chromaffin cells of the adrenal medulla that synthesize, store, metabolize, and usually, but not always, secrete catecholamines. Although pheochromocytomas are the cause of hypertension in only a small number of patients, they can precipitate life-threatening hypertension or cardiac arrhythmias caused by excessive and episodic catecholamine secretion. This article reviews the genetics, clinical presentation, and imaging of pheochromocytoma, with special emphasis on new positron emission tomographic radiopharmaceutical agents.

Keywords: (18)F-FDG; Gallium-68-DOTATATE; Iodine-123-MIBG; Paragangliomas; Phaeochromocytoma.

Publication types

Review