One pot preparation of silver nanoparticles decorated TiO2 mesoporous microspheres with enhanced antibacterial activity

Yuemei Chen; Yuanming Deng; Yitao Pu; Bijun Tang; Yikun Su; Jiaoning Tang

doi:10.1016/j.msec.2016.04.028

One pot preparation of silver nanoparticles decorated TiO2 mesoporous microspheres with enhanced antibacterial activity

Mater Sci Eng C Mater Biol Appl. 2016 Aug 1:65:27-32. doi: 10.1016/j.msec.2016.04.028. Epub 2016 Apr 10.

Authors

Yuemei Chen¹, Yuanming Deng², Yitao Pu³, Bijun Tang⁴, Yikun Su¹, Jiaoning Tang⁵

Affiliations

¹ Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China.
² Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China. Electronic address: ymdeng@szu.edu.cn.
³ College of Chemistry and Chemical Engineering, Shenzhen University, Shenzhen 518060, China.
⁴ Newnham College, Sidgwick Avenue, Cambridge CB3 9DF, United Kingdom.
⁵ Shenzhen Key Laboratory of Polymer Science and Technology, Guangdong Research Center for Interfacial Engineering of Functional Materials, College of Materials Science and Engineering, Shenzhen University, Shenzhen 518060, China. Electronic address: tjn@szu.edu.cn.

PMID: 27157724
DOI: 10.1016/j.msec.2016.04.028

Abstract

We report a simple "one-pot" solvothermal preparation of silver nanoparticles (Ag NPs) decorated mesoporous titania (TiO2) microspheres as an effective antibacterial agent. TBOT as Ti source was hydrolyzed and crystallized in media composed of acetic acid and ethanol, in which esterification catalyzed by TBOT occurred for in-situ "controlled water release". AgNO3 as Ag source was reduced by ethanol to form Ag NPs embedded in the TiO2 microspheres. The effect of AgNO3 and HAc on the morphology of Ag/TiO2 was investigated. The Ag/TiO2 with various Ag content showed excellent antibacterial activities with extremely low minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against Escherichia coli and Staphylococcus aureus when compared with colloidal Ag NPs.

Keywords: Antibacterial; Mesoporous; Silver nanoparticles; Solvothermal; Titania microspheres.

MeSH terms

Anti-Bacterial Agents / chemistry*
Anti-Bacterial Agents / pharmacology
Escherichia coli / drug effects
Metal Nanoparticles / chemistry*
Metal Nanoparticles / toxicity
Microbial Sensitivity Tests
Microscopy, Electron, Scanning
Microspheres*
Porosity
Silver / chemistry*
Silver Nitrate / chemistry
Staphylococcus aureus / drug effects
Titanium / chemistry*

Substances

Anti-Bacterial Agents
titanium dioxide
Silver
Silver Nitrate
Titanium