Comparative study of biological activities and multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa

J Enzyme Inhib Med Chem. 2016;31(sup1):203-208. doi: 10.1080/14756366.2016.1178247. Epub 2016 May 3.

Abstract

The multicomponent pattern and biological characterization of plant material are essential for pharmaceutical field, in the food supplements quality control procedures and to all plant-based products. These nutrients often show valuable effects related to their consumption due to the occurrence of secondary metabolites that show useful properties on health. In this framework, researches performed on this topic play a central role for human health and drug development process. The aim of this study was to compare phenolics and free anthraquinones multicomponent pattern of two wild Turkish species: Asphodeline anatolica and Potentilla speciosa using validated high-performance liquid chromatography-photogiode array (HPLC-PDA) assays, coupled to biological evaluation. Even if some variances related to biological and enzymatic inhibition activities can be ascribed to other phytochemicals, the reported data support traditional use of Asphodeline anatolica and Potentilla speciosa roots as valuable natural font for the development of novel natural-derived drug formulations and/or food supplements with health and nutritional benefits.

Keywords: Antioxidant; Asphodeline and Potentilla; HPLC-PDA method; anthraquinones and phenolics pattern; enzyme inhibitory effects.

Publication types

  • Comparative Study

MeSH terms

  • Anthraquinones / chemistry
  • Anthraquinones / isolation & purification
  • Anthraquinones / pharmacology*
  • Antioxidants / chemistry
  • Antioxidants / isolation & purification
  • Antioxidants / pharmacology*
  • Cholinesterases / metabolism
  • Chromatography, High Pressure Liquid
  • Dose-Response Relationship, Drug
  • Enzyme Inhibitors / chemistry
  • Enzyme Inhibitors / isolation & purification
  • Enzyme Inhibitors / pharmacology*
  • Humans
  • Liliaceae / chemistry*
  • Monophenol Monooxygenase / antagonists & inhibitors
  • Monophenol Monooxygenase / metabolism
  • Phenols / chemistry
  • Phenols / isolation & purification
  • Phenols / pharmacology*
  • Potentilla / chemistry*
  • Structure-Activity Relationship
  • Turkey
  • alpha-Amylases / antagonists & inhibitors
  • alpha-Amylases / metabolism
  • alpha-Glucosidases / metabolism

Substances

  • Anthraquinones
  • Antioxidants
  • Enzyme Inhibitors
  • Phenols
  • Monophenol Monooxygenase
  • Cholinesterases
  • alpha-Amylases
  • alpha-Glucosidases